Medically reviewed by Jessica Swirble, PharmDLast updated on March 26, 2025
Drug Information| | |
Buspirone is an effective and well-tolerated non-selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder (MDD) in adults.
Buspirone is most effective when taken as an adjunct to a diet that does not promote cholesterol levels or other high cholesterol-lowering effects.
It's also used to treat certain psychological disorders, such as generalized anxiety disorder (GAD) and major depressive disorder (MDD).
The drug may also be used to treat other conditions such as:
Buspirone is also prescribed to treat certain hormonal imbalances, such as and/or prostate cancer.
It's important to follow the dosage and duration of treatment as prescribed by your healthcare provider to ensure the best results.
Buspirone is generally considered an effective and well-tolerated non-selective serotonin reuptake inhibitor (SSRI) and is sometimes used off-label to treat certain mental health conditions.
It can be taken in combination with other medications as determined by your healthcare provider.
However, it's important to remember that this drug has the potential to cause serious side effects and should not be used to treat any other conditions that have been managed adequately.
Buspirone should not be used by individuals taking other medications that could interact with it, such as monoamine oxidase inhibitors (MAOIs) or other drugs that can increase the risk of seizures. Inform your healthcare provider about all the medications you take, including over-the-counter drugs, vitamins, and herbal supplements.
It's important to inform your healthcare provider about all the drugs you take, as well as any supplements or medicines that you buy without a prescription.
Buspirone should only be used by individuals who are already taking other non-selective medications that may affect its efficacy or cause side effects. It's also important to inform your healthcare provider about any other drugs or supplements you're taking, as some non-prescription products may interact with this drug.
It is important to discuss any existing medical conditions or medications being managed with your healthcare provider with regards to non-prescription medications or supplements, as well as other medications or treatments for mental health conditions.
Buspirone should be used under the guidance and supervision of a healthcare professional with the proper training and supervision of its use in the proper dosage and for the correct indication.
Follow the prescribed dosage and duration as instructed by your doctor and do not exceed the prescribed amount even if your symptoms improve. It's important to finish the full course as prescribed by your healthcare provider, even if your symptoms improve, to ensure the drug is still effective and safe for you to take.
Buspirone can cause side effects even in rare cases, including sexual dysfunction and breast tenderness.
It is important to note that this medication should not be used by individuals who are currently pregnant, breastfeeding, or utilizing any medications to treat mental health disorders, including Buspirone.
Buspirone should not be used by individuals who are currently nursing or may be using children or pets to handle medications that may interact with Buspirone.
It is important to discuss any pre-existing medical conditions or medications you are currently taking with your doctor before using this medication.
Buspirone can interact with other medications, including over-the-counter drugs, vitamins, and herbal supplements.
It can take four to eight weeks before you notice any improvement in your symptoms.
If you experience any unusual or severe side effects while using this medication, stop using the medication and contact your healthcare provider promptly.
Buspar has been shown to cause some side effects. Talk to your health care provider if these mild reactions do not go away within a few days.
Common side effects reported from Buspar use include:
This is not a complete list of adverse reactions caused by Buspar. Call your doctor immediately if you experience a skin rash; hives; swelling of the eyes, face, mouth, throat, or lips; agitation; severe vomiting; blurred vision; a fast or irregular heartbeat; or uncontrollable shaking. Call your doctor immediately if you have severe muscle stiffness, twitching, seizures, hallucinations, or fever.
As with all prescription medications, be sure to inform the prescribing doctor about any medical conditions you have been previously diagnosed with and any medication/ supplements you are currently taking before taking Buspar. Buspar can interact with other forms of medication, causing potentially serious side effects. Specifically, inform your health care provider if you have or have had liver or kidney disease or a history of substance abuse. Finally, let your doctor know if you are pregnant or plan on becoming pregnant before starting treatment with this medication.
This medication has been approved for use in adults 18 years or older. Buspar is not approved for use in children under 18 years of age. Use of this medication is not recommended during pregnancy.As with all prescription medications, be careful if you have or have had liver or kidney disease or a history of liver or kidney disease. This drug has been approved for use in adults. Use of this medication should only be done with your health care provider forownability or indefinite dosage. If you have liver or kidney disease, kidney disease, or a history of liver or kidney disease, consult your doctor right away if you need to know certain dietary supplements to take after taking this medication.
This drug is not recommended for use in pregnant women or women who are pregnant or can use other forms of medication. Food and Drug Administration (FDA) approved for prescription drug treatment in the treatment of depression; anxiety; panic disorder; social anxiety disorder; obsessive-compulsive disorder; posttraumatic stress disorder; and generalized anxiety disorder. Buspar is not approved for use in adults under the age of 18 years. This medication is not recommended for use in children under 18 years of age.
Use of this medication for well over a year has been shown to be associated with a lower risk of psychiatric side effects. However, studies of this drug in children and adults are still in the early stages. Some people may experience worsening depression or suicidal thoughts. Many people also reported feeling restless, more likely to have difficulty sleeping, or other mental health concerns. However, these effects were mild and temporary. It is important to disclose your psychiatric history to your health care provider, as early signs of depression may include worsening symptoms of suicidal thoughts or getting up in a deep sleep at night, or thoughts that the body is more vulnerable to falls and other injuries. It is not recommended for use in children under the age of 18 years.
This medication may cause an increase in blood pressure. If you experience an erection that lasts more than four hours, you should consult a doctor immediately. If you have heart problems, blood circulation may be affected, you should see your doctor immediately, and tell your health care provider if you have an irregular heartbeat, fever, confusion, chills, muscle cramps, or any other mental health concerns.
In addition, some people have reported a decrease in bone mineral density and a higher risk of fractures. If you are at risk, low sexual desire or ability, anxiety, or depression, you should disclose your risk to your health care provider.
Other medications have been studied for their use in the treatment of depression. These medications include phenelzine, tranylcypromine, selegiline, and isocarboxazid.
This medication has been approved for use in the treatment of attention-deficit hyperactivity disorder (ADHD).
These medications include amitriptyline, amoxapine, desipramine, doxepin, imipramine, imatinib, nelfinavir, or valsartan.
Buspirone (brand name BuSpar) is a type of anxiolytic. It is an oral tablet that you take as a pill. It works by making you feel less anxious and less tense. When taken as needed, it can be prescribed to help with a variety of anxiety disorders.
Common side effects of Buspirone may include nausea, vomiting, or stomach pain. These are not common, but your healthcare provider may recommend them for other conditions. Be sure to tell your healthcare provider about any other medications, vitamins, or herbal supplements you are taking before starting Buspirone.
Buspirone is also sometimes used off label to treat certain mental health disorders. This can be a safe, effective, and helpful option for people who have a mental health condition or are currently taking certain medications.
Buspirone is not approved by the Food and Drug Administration (FDA) for use in pregnancy or while breastfeeding. While it is not approved for use during pregnancy, you should talk to your healthcare provider about any other medications you are taking before starting Buspirone. Discuss any possible side effects and risks with your healthcare provider.
Buspirone is available in generic and brand names like BuSpar, Buspar Generic, and Buspar Brand. BuSpar and BuSpar Brand are not FDA approved for use in children under age 18.
Brand Name: BuSpar
Manufacturer: Mylan Pharmaceuticals
Active Ingredient: Bupropion Hydrochloride.
Common Side Effects of BuSpar:
Headache, flushing, stuffy or runny nose
Somnolence or dizziness, feeling anxious, nervousness, or racing heart
Nausea, vomiting, dizziness, dry mouth, constipation
Somnolence or dizziness, nausea, sweating, tiredness, and drowsiness
Sore throat, back pain, muscle stiffness or spasms, and swelling in the limbs
Nausea, vomiting, diarrhea, or stomach pain
Somnolence or dizziness, nausea, stomach ache, feeling sleepy, and dizziness
Somnolence or dizziness, feeling restless, anxious, irritable, agitated, or fidgety, anxiety, or excitement
Headache, flushing, stuffy or runny nose, sweating, tiredness, and drowsiness
Common side effects of BuSpar may include drowsiness, headache, dizziness, drowsiness, sweating, or feeling lightheaded, blurred vision, and increased sweating. These are not common, but your healthcare provider may recommend these for other conditions.
Buspar is used to treat anxiety. It helps people who are struggling with social anxiety disorder to function and stay organized. This medication helps to decrease the severity of symptoms and reduce the frequency of attacks. It is also used to treat panic disorder in some people. However, buspar is not FDA approved for this use.
Buspirone can be used in the following ways:
Buspar can also be taken with or without food.
Buspar may also be taken by people who have certain medical conditions, including liver disease, kidney disease, or if they are on other medications.
Buspar can be taken with or without food.
Buspar is only available in the United States. It is not FDA approved for use in the United States.
Buspar may be used to treat panic disorder. It can be used to treat symptoms of panic disorder. This medication works by helping to reduce the amount of anxiety that you experience.
Buspar may also be used to treat symptoms of anxiety disorder. This medication may help to decrease symptoms of anxiety such as panic attacks and tension, or reduce feelings of anxiety.
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